DOTTIKON EXCLUSIVE SYNTHESIS is the specialist for hazardous reactions. Hazardous reaction technologies are used for the manufacturing (grams to multi-tons) of exclusive APIs and high-quality intermediates for the world's leading pharmaceutical and chemical companies. DOTTIKON ES' safety culture and dedicated equipment allow the use of hazardous reactions to shortcut syntheses, improve quality, and reduce costs. Hazardous reactions performed at DOTTIKON ES are comprised of four categories: highly exothermic processes, thermally or mechanically unstable compounds, highly reactive compounds and high-potent compounds. Core strengths are: azide chemistry, oxidations, nitrations, alkylations, hydrides, catalytic hydrogenations (hetero-/homogeneous), continuous reactions technologies and low temperature reactions.