Euticals is an Italian group of companies dealing with Custom Synthesis and production of Intermediates and Active Pharmaceutical Ingredients. All Euticals plants comply with current GMP regulations and 3 out 4 are FDA acceptable with no 483. AMBROSIA is a small chemical plant that produces the quantities necessary for the clinical development of New Chemical Entities from grams up to few hundred kgs. It includes also the R&D facilities where new production processes are created and optimised and where all Custom Synthesis services are provided. PROBIOSINT is famous for the production of mononucleotides but from here has developed the manufacture of new sophisticated antimetabolite drugs for oncology in segregated facilities. The technologies available in PROBIOSINT range from chemical synthesis to enzymatic and fermentation processes in the realm of new biotechnologies. EUTICALS and PROCHISA are relatively big chemical plants that can produce the large quantities needed in the commercial phase employing sophisticated and difficult-to-handle technologies.