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An Aldol condensation is an organic reaction in which an enolate ion reacts with a carbonyl compound to form a ß-hydroxyaldehyde or ß-hydroxyketone, followed by dehydration to give a conjugated enone.

Aldol condensations are important in organic synthesis, providing a good way to form carbon–carbon bonds. The Robinson annulation reaction sequence features an aldol condensation; the Wieland-Miescher ketone product is an important starting material for many organic syntheses. Aldol condensations are also commonly discussed in university level organic chemistry classes as a good bond-forming reaction that demonstrates important reaction mechanisms.[1][2][3] In its usual form, it involves the nucleophilic addition of a ketone enolate to an aldehyde to form a ß-hydroxy ketone, or "aldol" (aldehyde + alcohol), a structural unit found in many naturally occurring molecules and pharmaceuticals.[4][5][6]